A single intravenous injection of cyclosporin A–loaded lipid nanocapsules prevents retinopathy of prematurity

URN to cite this document:: urn:nbn:de:bvb:355-epub-532326
DOI to cite this document:: 10.5283/epub.53232

Bohley, Marilena ; Dillinger, Andrea E. ; Schweda, Frank ; Ohlmann, Andreas ; Braunger, Barbara M. ; Tamm, Ernst R. ; Goepferich, Achim

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Date of publication of this fulltext: 17 Nov 2022 13:28

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Abstract

Retinopathy of prematurity (ROP) is a retinal disease that threatens the vision of prematurely born infants. Severe visual impairment up to complete blindness is caused by neovascularization and inflammation, progressively destroying the immature retina. ROP primarily affects newborns in middle- and low-income countries with limited access to current standard treatments such as intraocular drug ...