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Impact of Melatonin on RAW264.7 Macrophages during Mechanical Strain

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Paddenberg, Eva ; Forneck, Anne ; Widbiller, Matthias ; Smeda, Martyna ; Jantsch, Jonathan ; Proff, Peter ; Kirschneck, Christian ; Schröder, Agnes
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 28 Nov 2022 14:24


The concentration of melatonin is elevated during the night when patients mainly wear removable orthodontic appliances. Next to periodontal ligament fibroblasts and osteoblasts, macrophages react to mechanical strain with an increased expression of inflammatory mediators. Here, we investigated the impact of melatonin on RAW264.7 macrophages exposed to tensile or compressive strain occurring ...


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