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Impact of Melatonin on RAW264.7 Macrophages during Mechanical Strain

URN to cite this document:
urn:nbn:de:bvb:355-epub-532763
DOI to cite this document:
10.5283/epub.53276
Paddenberg, Eva ; Forneck, Anne ; Widbiller, Matthias ; Smeda, Martyna ; Jantsch, Jonathan ; Proff, Peter ; Kirschneck, Christian ; Schröder, Agnes
[img]License: Creative Commons Attribution 4.0
PDF - Published Version
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Date of publication of this fulltext: 28 Nov 2022 14:24



Abstract

The concentration of melatonin is elevated during the night when patients mainly wear removable orthodontic appliances. Next to periodontal ligament fibroblasts and osteoblasts, macrophages react to mechanical strain with an increased expression of inflammatory mediators. Here, we investigated the impact of melatonin on RAW264.7 macrophages exposed to tensile or compressive strain occurring ...

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