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Practical Relevance of Institutional Guidelines in Translational Large Animal Studies of Cartilage Repair—A Multidisciplinary Survey

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Riedl, Moritz ; Rupp, Markus ; Walter, Nike ; Henssler, Leopold ; Kerschbaum, Maximilian ; Popp, Daniel ; Vadalà, Gianluca ; Alt, Volker ; Docheva, Denitsa ; Pfeifer, Christian G.
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Date of publication of this fulltext: 23 Dec 2022 07:44


Background and Objective: Translational large animal models are inevitable to transfer cartilage repair methods into clinical practice. Guidelines for these trials have been published by guiding agencies (FDA, ASTM, EMEA) including recommendations for study descriptors and study outcomes. However, practical adherence to these recommendations is not achieved in all aspects. This study includes an ...


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