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Human Infections with Borna Disease Virus 1 (BoDV-1) Primarily Lead to Severe Encephalitis: Further Evidence from the Seroepidemiological BoSOT Study in an Endemic Region in Southern Germany

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Bauswein, Markus ; Eidenschink, Lisa ; Knoll, Gertrud ; Neumann, Bernhard ; Angstwurm, Klemens ; Zoubaa, Saida ; Riemenschneider, Markus J. ; Lampl, Benedikt M. J. ; Pregler, Matthias ; Niller, Hans Helmut ; Jantsch, Jonathan ; Gessner, André ; Eberhardt, Yvonne ; Huppertz, Gunnar ; Schramm, Torsten ; Kühn, Stefanie ; Koller, Michael ; Drasch, Thomas ; Ehrl, Yvonne ; Banas, Bernhard ; Offner, Robert ; Schmidt, Barbara ; Banas, Miriam C.
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Date of publication of this fulltext: 12 Jan 2023 14:01


More than 40 human cases of severe encephalitis caused by Borna disease virus 1 (BoDV-1) have been reported to German health authorities. In an endemic region in southern Germany, we conducted the seroepidemiological BoSOT study (“BoDV-1 after solid-organ transplantation”) to assess whether there are undetected oligo- or asymptomatic courses of infection. A total of 216 healthy blood donors and ...


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