Diagnostic Value of Diffusion-Weighted Imaging with Background Body Signal Suppression (DWIBS) for the Pre-Therapeutic Loco-Regional Staging of Cervical Cancer: A Feasibility and Interobserver Reliability Study

URN zum Zitieren dieses Dokuments:

urn:nbn:de:bvb:355-epub-535501 Copy

DOI zum Zitieren dieses Dokuments:

10.5283/epub.53550 Copy

Schleder, Stephan ; May, Matthias ; Scholz, Carsten ; Dinkel, Johannes ; Strotzer, Quirin David ; Einspieler, Ingo ; Dollinger, Marco ; Schreyer, Andreas G. ; Grassinger, Jochen ; Schicho, Andreas

Lizenz: Creative Commons Namensnennung 4.0 International PDF - Veröffentlichte Version (1MB)

Veröffentlichungsdatum dieses Volltextes: 18 Jan 2023 09:44

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Alternative Links zum Volltext:DOIVerlag

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Details

Dokumentenart:	Artikel
Open Access Art:	Gold (ohne APC)
Titel eines Journals oder einer Zeitschrift:	Current Oncology
Verlag:	MDPI
Band:	30
Nummer des Zeitschriftenheftes oder des Kapitels:	1
Seitenbereich:	S. 1164-1173
Datum:	13 Januar 2023
Institutionen:	Medizin > Lehrstuhl für Röntgendiagnostik
Identifikationsnummer:	Wert Typ 10.3390/curroncol30010089 DOI
Stichwörter / Keywords:	MRI; DWIBS; cervical cancer; staging
Dewey-Dezimal-Klassifikation:	600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin
Status:	Veröffentlicht
Begutachtet:	Ja, diese Version wurde begutachtet
An der Universität Regensburg entstanden:	Ja
Dokumenten-ID:	53550

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Zusammenfassung

Background: Cervical cancer is one of the leading causes of cancer-related deaths and the fourth most common cancer among women worldwide. Magnetic resonance imaging (MRI) is the modality of choice for loco-regional staging of cervical cancer in the primary diagnostic workup beginning with at least stage IB. Methods: We retrospectively analyzed 16 patients with histopathological proven ...

Zusammenfassung

Background:
Cervical cancer is one of the leading causes of cancer-related deaths and the fourth most common cancer among women worldwide. Magnetic resonance imaging (MRI) is the modality of choice for loco-regional staging of cervical cancer in the primary diagnostic workup beginning with at least stage IB.
Methods:
We retrospectively analyzed 16 patients with histopathological proven cervical cancer (FIGO IB1–IVA) for the diagnostic accuracy of standard MRI and standard MRI with diffusion-weighted imaging with background body signal suppression (DWIBS) for the correct pre-therapeutic assessment of the definite FIGO category.
Results:
In 7 out of 32 readings (22%), DWIBS improved diagnostic accuracy. With DWIBS, four (13%) additional readings were assigned the correct major (I–IV) FIGO stages pre-therapeutically. Interobserver reliability of DWIBS was weakest for parametrial infiltration (k = 0.43; CI-95% 0.00–1.00) and perfect for tumor size <2 cm, infiltration of the vaginal lower third, infiltration of adjacent organs and loco-regional nodal metastases (k = 1.000; CI-95% 1.00–1.00).
Conclusions:
The pre-therapeutic staging of cervical cancer has a high diagnostic accuracy and interobserver reliability when using standard MRI but can be further optimized with the addition of DWIBS sequences when reporting is performed by an experienced radiologist.

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Metadaten zuletzt geändert: 09 Mai 2023 12:44

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