Particle-based delivery of the HIV envelope protein

URN to cite this document:: urn:nbn:de:bvb:355-epub-537864
DOI to cite this document:: 10.5283/epub.53786

Asbach, Benedikt

; Wagner, Ralf

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Date of publication of this fulltext: 16 Feb 2023 12:44

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Abstract

Purpose of review: A major focus in HIV vaccine research is the development of suitable antigens that elicit broadly neutralizing antibody responses targeting HIV's envelope protein (Env). Delivery of Env in a repetitive manner on particle-based carriers allows higher-avidity interactions and is therefore expected to efficiently engage B cells thus leading to affinity maturation that results in ...