Liposome-based high-throughput and point-of-care assays toward the quick, simple, and sensitive detection of neutralizing antibodies against SARS-CoV-2 in patient sera

URN to cite this document:: urn:nbn:de:bvb:355-epub-538143
DOI to cite this document:: 10.5283/epub.53814

Streif, Simon ; Neckermann, Patrick ; Spitzenberg, Clemens ; Weiss, Katharina ; Hoecherl, Kilian ; Kulikowski, Kacper ; Hahner, Sonja ; Noelting, Christina ; Einhauser, Sebastian

; Peterhoff, David

; Asam, Claudia ; Wagner, Ralf

; Baeumner, Antje J.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 21 Feb 2023 06:37

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Abstract

The emergence of severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) in 2019 caused an increased interest in neutralizing antibody tests to determine the immune status of the population. Standard live-virus-based neutralization assays such as plaque-reduction assays or pseudovirus neutralization tests cannot be adapted to the point-of-care (POC). Accordingly, tests quantifying ...