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Adenoid cystic carcinoma of the salivary glands: a pilot study of potential therapeutic targets and characterization of the immunological tumor environment and angiogenesis

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Michaelides, Ioannis ; Künzel, Julian ; Ettl, Tobias ; Beckhove, Philipp ; Bohr, Christopher ; Brochhausen, Christoph ; Mamilos, Andreas
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 08 Mar 2023 06:48

This publication is part of the DEAL contract with Springer.


Background Adenoid cystic carcinoma (ACC) is a rare type of cancer commonly occurring in salivary glands. It is characterized by slow but infiltrative growth, nerve infiltration and overall poor prognosis, with late recurrence and distant metastasis. The treatment of ACC is still limited to surgery and/or (adjuvant) radiotherapy. Till now no promising systemic therapy option exists. However, ...


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