Barth, A., Neubert, K., Schwarz, G., Fischer, G., Dove, Stefan and Franke, R. (1985) Enzymatic Hydrolyses of Alanyl-alanine-anilides by Dipeptidyl Peptidase IV. In: Seydel, J. K., (ed.) QSAR and Strategies in the Design of Bioactive Compounds - Proceedings of the 5th European Symposium on QSAR. Verlag Chemie, Weinheim, 318 - 321. ISBN 3-527-26306-3; 0-89573-433-8.
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Abstract
A no. of m- and p-substituted Ala-Ala-anilides were enzymically hydrolyzed by dipeptidyl peptidase IV. The catalytic consts., log kcat, are pos. related to Hammett's s-values. In another approach, the electronic effects were represented by the components of dipole moment vectors resulting from quantum chem. calcns. Conformation anal. based on the correlation of log kcat with these parameters ...
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| Item type: | Book section | ||||
|---|---|---|---|---|---|
| Date: | 1985 | ||||
| Institutions: | Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||
| Identification Number: |
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| Dewey Decimal Classification: | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||
| Status: | Published | ||||
| Refereed: | No, this document will not be refereed | ||||
| Created at the University of Regensburg: | No | ||||
| Item ID: | 5390 |
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