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Elongation factor 1 is a component of the Arabidopsis RNA polymerase II elongation complex and associates with a subset of transcribed genes

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Markusch, Hanna ; Michl‐Holzinger, Philipp ; Obermeyer, Simon ; Thorbecke, Claudia ; Bruckmann, Astrid ; Babl, Sabrina ; Längst, Gernot ; Osakabe, Akihisa ; Berger, Frédéric ; Grasser, Klaus D.
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Date of publication of this fulltext: 08 Mar 2023 06:31


Elongation factors modulate the efficiency of mRNA synthesis by RNA polymerase II (RNAPII) in the context of chromatin, thus contributing to implement proper gene expression programmes. The zinc-finger protein elongation factor 1 (ELF1) is a conserved transcript elongation factor (TEF), whose molecular function so far has not been studied in plants. Using biochemical approaches, we examined the ...


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