![]() | PDF (230kB) - Repository staff only |
Abstract
Impromidine (IMP) and arpromidine (ARP)-derived guanidines are more potent and efficacious guinea pig (gp) histamine H2-receptor (gpH2R) than human (h) H2R agonists and histamine H1-receptor (H1R) antagonists with preference for hH1R relative to gpH1R. We examined NG-acylated imidazolylpropylguanidines (AIPGs), which are less basic than guanidines, at hH2R, gpH2R, rat H2R (rH2R), hH1R, and gpH1R ...

Owner only: item control page