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Some Problems of the Interpretation of Receptorologic Data in QSAR Work

Dove, Stefan ; Franke, R. Fauchere, J. L. , eds.



Abstract

An extended model of the b-adrenergic receptor and adenylate cyclase activation by b-agonists, including receptor conformational changes and ternary complex formation with effector G protein are used to illustrate problems in QSAR.


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