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Galleria mellonella as an alternative in vivo model to study implant‐associated fungal infections

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Mannala, Gopala K. ; Rupp, Markus ; Walter, Nike ; Scholz, Konstantin J. ; Simon, Michaela ; Riool, Martijn ; Alt, Volker
Date of publication of this fulltext: 04 May 2023 07:04

This publication is part of the DEAL contract with Wiley.


Fungal implant-associated bone infections are rare but difficult to treat and often associated with a poor outcome for patients. Candida species account for approximately 90% of all fungal infections. In vivo biofilm models play a major role to study biofilm development and potential new treatment options; however, there are only a very few in vivo models to study fungi-associated biofilms. ...


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