A20 as a Potential New Tool in Predicting Recurrence and Patient’s Survival in Oral Squamous Cell Carcinoma

URN to cite this document:: urn:nbn:de:bvb:355-epub-542090
DOI to cite this document:: 10.5283/epub.54209

Spoerl, Steffen ; Erber, Ramona

; Gerken, Michael ; Taxis, Juergen

; Ludwig, Nils

; Nieberle, Felix ; Biermann, Niklas ; Geppert, Carol Immanuel ; Ettl, Tobias

; Hartmann, Arndt ; Beckhove, Philipp

; Reichert, Torsten E. ; Spanier, Gerrit

; Spoerl, Silvia

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 11 May 2023 12:47

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Abstract

A20, known as a potent inhibitor of NF-κB signaling, has been characterized in numerous clinical as well as preclinical studies. Recently, especially in various malignant diseases, the prognostic and therapeutic relevance of A20 was investigated. In oral squamous cell carcinoma (OSCC) however, the characterization of A20 is uncharted territory. We analyzed a tissue microarray (TMA) of 229 ...