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CCN2/CTGF tip the balance of growth factors towards TGF-β2 in primary open-angle glaucoma

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Dillinger, Andrea E. ; Kuespert, Sabrina ; Seleem, Amin A. ; Neuendorf, Jakob ; Schneider, Magdalena ; Fuchshofer, Rudolf
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 06 Jun 2023 06:29


TGF-β2 is the predominant TGF-β isoform within the eye. One function of TGF-β2 is to provide the eye with immune protection against intraocular inflammation. The beneficial function of TGF-β2 within the eye must be under tight control of a network of different factors. A disbalance of the network can result in different eye diseases. In Primary Open-Angle Glaucoma (POAG), one of the leading ...


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