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In situ veritas: combining omics and multiplex imaging can facilitate the detection and characterization of cell-cell interactions in tissues

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Ritter, Uwe
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Date of publication of this fulltext: 06 Jun 2023 08:46


In 1898, microscopic examinations were used to study changes in lymphoid tissues and cell distribution in pathological settings (1). More than 100 years after these first discoveries, the complexity of lymphoid organ composition and the existence of distinct immune-cell subpopulations with a diverse set of functions has been described. For the adaptive immune system to function efficiently, ...


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