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Role of Estrogen Receptor β, G-Protein Coupled Estrogen Receptor and Estrogen-Related Receptors in Endometrial and Ovarian Cancer

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Schüler-Toprak, Susanne ; Skrzypczak, Maciej ; Gründker, Carsten ; Ortmann, Olaf ; Treeck, Oliver
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 Jun 2023 06:37


Ovarian and endometrial cancers are affected by estrogens and their receptors. It has been long known that in different types of cancers, estrogens activate tumor cell proliferation via estrogen receptor α (ERα). In contrast, the role of ERs discovered later, including ERβ and G-protein-coupled ER (GPER1), in cancer is less well understood, but the current state of knowledge indicates them to ...


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