Role of Estrogen Receptor β, G-Protein Coupled Estrogen Receptor and Estrogen-Related Receptors in Endometrial and Ovarian Cancer

URN to cite this document:: urn:nbn:de:bvb:355-epub-543424
DOI to cite this document:: 10.5283/epub.54342

Schüler-Toprak, Susanne

; Skrzypczak, Maciej ; Gründker, Carsten ; Ortmann, Olaf

; Treeck, Oliver

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 Jun 2023 06:37

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Abstract

Ovarian and endometrial cancers are affected by estrogens and their receptors. It has been long known that in different types of cancers, estrogens activate tumor cell proliferation via estrogen receptor α (ERα). In contrast, the role of ERs discovered later, including ERβ and G-protein-coupled ER (GPER1), in cancer is less well understood, but the current state of knowledge indicates them to ...