Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution

URN to cite this document:: urn:nbn:de:bvb:355-epub-544634
DOI to cite this document:: 10.5283/epub.54463

Elsner, Felix ; Hoffmann, Martin ; Fahrioglu‐Yamaci, Rezan ; Czyz, Zbigniew ; Feliciello, Giancarlo ; Mederer, Tobias

; Polzer, Bernhard ; Treitschke, Steffi ; Rümmele, Petra ; Weber, Florian

; Wiesinger, Hellmuth ; Robold, Tobias ; Sziklavari, Zsolt ; Sienel, Wulf ; Hofmann, Hans‐Stefan ; Klein, Christoph A.

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Oct 2023 13:38

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Abstract

In melanoma, immunocytology (IC) after sentinel lymph node disaggregation not only enables better quantification of disseminated cancer cells (DCCs) than routine histopathology (HP) but also provides a unique opportunity to detect, isolate, and analyse these earliest harbingers of metachronous metastasis. Here, we explored lymph node IC in non-small cell lung cancer (NSCLC). For 122 NSCLC ...