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Disseminated cancer cells detected by immunocytology in lymph nodes of NSCLC patients are highly prognostic and undergo parallel molecular evolution

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Elsner, Felix ; Hoffmann, Martin ; Fahrioglu‐Yamaci, Rezan ; Czyz, Zbigniew ; Feliciello, Giancarlo ; Mederer, Tobias ; Polzer, Bernhard ; Treitschke, Steffi ; Rümmele, Petra ; Weber, Florian ; Wiesinger, Hellmuth ; Robold, Tobias ; Sziklavari, Zsolt ; Sienel, Wulf ; Hofmann, Hans‐Stefan ; Klein, Christoph A.
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 05 Oct 2023 13:38

This publication is part of the DEAL contract with Wiley.


In melanoma, immunocytology (IC) after sentinel lymph node disaggregation not only enables better quantification of disseminated cancer cells (DCCs) than routine histopathology (HP) but also provides a unique opportunity to detect, isolate, and analyse these earliest harbingers of metachronous metastasis. Here, we explored lymph node IC in non-small cell lung cancer (NSCLC). For 122 NSCLC ...


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