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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-544964
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.54496
Zusammenfassung
Conventional 2D cultures are commonly used in cancer research though they come with limitations such as the lack of microenvironment or reduced cell heterogeneity. In this study, we investigated in what respect a scaffold-based (Matrigel™) 3D culture technique can ameliorate the limitations of 2D cultures. NGS-based bulk and single-cell sequencing of matched pairs of 2D and 3D models showed an ...
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