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Pathogenic Relationships in Cystic Fibrosis and Renal Diseases: CFTR, SLC26A9 and Anoctamins

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Kunzelmann, Karl ; Ousingsawat, Jiraporn ; Kraus, Andre ; Park, Julien H. ; Marquardt, Thorsten ; Schreiber, Rainer ; Buchholz, Björn
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Date of publication of this fulltext: 30 Aug 2023 08:56


The Cl−-transporting proteins CFTR, SLC26A9, and anoctamin (ANO1; ANO6) appear to have more in common than initially suspected, as they all participate in the pathogenic process and clinical outcomes of airway and renal diseases. In the present review, we will therefore concentrate on recent findings concerning electrolyte transport in the airways and kidneys, and the role of CFTR, SLC26A9, and ...


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