Alternative Links zum Volltext:
| Dokumentenart: | Patent | ||||||
|---|---|---|---|---|---|---|---|
| Seitenbereich: | 25 pp | ||||||
| Datum: | 2003 | ||||||
| Zusätzliche Informationen (Öffentlich): | CAN 139:159041 78-7 Inorganic Chemicals and Reactions Patent 20030807 160734-53-2P; 434933-86-5P; 434933-97-8P; 438583-76-7P; 438583-80-3P Role: PAC (Pharmacological activity), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (prepn. of water-sol. platinum porphyrin amine complexes with high tumor selectivity for use in photodynamic therapy); 434933-87-6P; 434933-89-8P; 434933-90-1P; 434933-93-4P; 434933-94-5P; 434933-95-6P; 434933-96-7P; 434933-98-9P; 434933-99-0P; 434934-00-6P; 434934-01-7P; 434934-02-8P; 434934-04-0P; 434934-05-1P; 434934-06-2P; 438583-42-7P; 438583-44-9P; 438583-46-1P; 438583-48-3P; 438583-52-9P; 438583-54-1P; 438583-56-3P; 438583-59-6P; 438583-62-1P; 438583-64-3P; 438583-66-5P; 438583-68-7P; 438583-70-1P; 438583-72-3P; 438583-74-5P; 438583-78-9P; 438583-82-5P; 438583-84-7P; 438583-86-9P; 438583-88-1P; 438583-90-5P; 438583-92-7P; 438583-94-9P; 438583-96-1P; 438583-98-3P; 438584-00-0P; 438584-02-2P; 438584-04-4P; 438584-06-6P; 438584-08-8P; 438584-10-2P Role: PAC (Pharmacological activity), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (reactant for prepn. of water-sol. platinum porphyrin amine complexes with high tumor selectivity for use in photodynamic therapy); 13965-31-6 ((2,2'-Bipyridine)dichloroplatinum); 38780-40-4 (Dichloro(trans-1,2-diaminocyclohexane)platinum); 149020-66-6; 161096-40-8; 434933-82-1; 434933-83-2; 438245-16-0 Role: RCT (Reactant), RACT (Reactant or reagent) (reactant for prepn. of water-sol. platinum porphyrin amine complexes with high tumor selectivity for use in photodynamic therapy) A2 US 2002-353585 20020201 | ||||||
| Institutionen: | Chemie und Pharmazie > Institut für Anorganische Chemie Chemie und Pharmazie > Institut für Pharmazie > Lehrstuhl Pharmazeutische / Medizinische Chemie II (Prof. Buschauer) | ||||||
| Identifikationsnummer: |
| ||||||
| Stichwörter / Keywords: | Porphyrins; Role: PAC (Pharmacological activity), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (platinum complexes prepn. of water-sol. platinum porphyrin amine complexes with high tumor selectivity for use in photodynamic therapy); Antitumor agents; Bladder; Photodynamic therapy; Photosensitizers; Phototoxicity (prepn. of water-sol. platinum porphyrin amine complexes with high tumor selectivity for use in photodynamic therapy); platinum porphyrin amine prepn antitumor photodynamic therapy; hematoporphyrin platinum amine prepn antitumor photodynamic therapy | ||||||
| Dewey-Dezimal-Klassifikation: | 500 Naturwissenschaften und Mathematik > 570 Biowissenschaften, Biologie 500 Naturwissenschaften und Mathematik > 540 Chemie | ||||||
| Status: | Veröffentlicht | ||||||
| Begutachtet: | Ja, diese Version wurde begutachtet | ||||||
| An der Universität Regensburg entstanden: | Ja | ||||||
| Dokumenten-ID: | 5471 |
Zusammenfassung
The invention relates to the prepn. of novel, water-sol. porphyrin platinum compds. of the tetraarylporphyrin platinum type or of the hematoporphyrin platinum type in which a platinum diamine is bonded to pendant arm/arms of the porphyrin. with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases. These compds. have high tumor selectivity and are proposed ...
Zusammenfassung
The invention relates to the prepn. of novel, water-sol. porphyrin platinum compds. of the tetraarylporphyrin platinum type or of the hematoporphyrin platinum type in which a platinum diamine is bonded to pendant arm/arms of the porphyrin. with high tumor selectivity and their use for the treatment of benign and malignant tumor diseases. These compds. have high tumor selectivity and are proposed for use in the treatment of benign and malignant tumor diseases. In particular, the compds. are suitable for photodynamic antitumor therapy. Thus, the tetraarylporphyrin platinum complex (I) and the hematoporphyrin platinum complex (II) and related complexes were prepd. and cytotoxic/phototoxic antiproliferative activity against model bladder cancer cell lines TCC-SUP and J82 measured.
Metadaten zuletzt geändert: 24 Mai 2018 10:10
Nur für Besitzer und Autoren: Kontrollseite des Eintrags
Altmetric