Development of a parenterally administrable hydrosol preparation of the
third generation platinum complex
[(+-)-1,2-bis(4-fluorophenyl)ethylenediamine]dichloroplatinum(II). Part 1. Preparation and studies on the stability and antitumor activity
Gust, Ronald, Bernhardt, Günther, Spruss, Thilo, Krauser, Rudolf, Koch, Marion, Schönenberger, Helmut, Bauer, Kurt-Heinz, Schertl, Sabine and Lu, Zhi
(1995)
Development of a parenterally administrable hydrosol preparation of the Date of publication of this fulltext: 05 Aug 2009 13:50
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| Item type | Article | ||||
| Journal or Publication Title | Archiv der Pharmazie (Weinheim, Germany) | ||||
| Volume: | 328 | ||||
|---|---|---|---|---|---|
| Number of Issue or Book Chapter: | 9 | ||||
| Page Range: | pp. 645-653 | ||||
| Date | 1995 | ||||
| Additional Information (public) | CAN 124:336 1-6 Pharmacology 163168-43-2 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), BIOL (Biological study) (prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); 125948-98-3 Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), RCT (Reactant), BIOL (Biological study), RACT (Reactant or reagent) (prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); 105990-74-7P Role: BAC (Biological activity or effector, except adverse), BSU (Biological study, unclassified), SPN (Synthetic preparation), THU (Therapeutic use), BIOL (Biological study), PREP (Preparation), USES (Uses) (prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); 7647-14-5 (Sodium chloride); 106392-12-5 (Pluronic F 68) Role: BUU (Biological use, unclassified), BIOL (Biological study), USES (Uses) (prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II) | ||||
| Institutions | Chemistry and Pharmacy > Institute of Pharmacy > Alumni or Retired Professors > Prof. Schönenberger Chemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry II (Prof. Buschauer) | ||||
| Identification Number |
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| Keywords | Pharmaceutical dosage forms (hydrosols, prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); Neoplasm inhibitors (mammary gland, prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); Mammary gland (neoplasm, inhibitors, prepn., stability, and antitumor activity of parenterally administrable hydrosol of [bis(fluorophenyl)ethylenediamine]dichloroplatinum(II); platinum complex prepn stability neoplasm inhibition; fluorophenylethylenediaminedichloroplatinum complex prepn stability neoplasm inhibition | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences 500 Science > 540 Chemistry & allied sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Partially | ||||
| Item ID | 5477 |
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