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Fecal short chain fatty acids and urinary 3-indoxyl sulfate do not discriminate between patients with Crohn´s disease and ulcerative colitis and are not of diagnostic utility for predicting disease severity

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Tews, Hauke Christian ; Elger, Tanja ; Gunawan, Stefan ; Fererberger, Tanja ; Sommersberger, Stefanie ; Loibl, Johanna ; Huss, Muriel ; Liebisch, Gerhard ; Müller, Martina ; Kandulski, Arne ; Buechler, Christa
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Date of publication of this fulltext: 05 Oct 2023 12:00


Background Urinary 3-indoxyl sulfate levels as well as fecal short chain fatty acid (SCFA) concentrations are surrogate markers for gut microbiota diversity. Patients with inflammatory bowel diseases (IBDs) and patients with primary sclerosing cholangitis (PSC), a disease closely associated with IBD, have decreased microbiome diversity. In this paper, the fecal SCFAs propionate, acetate, ...


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