Short-term effects of etifoxine on human gut microbiome in healthy men

URN to cite this document:: urn:nbn:de:bvb:355-epub-551404
DOI to cite this document:: 10.5283/epub.55140

Manook, André ; Baghai, Thomas C. ; Riebel, Marco ; Nothdurfter, Caroline ; Schwarzbach, Jens Volkmar ; Gessner, André

; Rupprecht, Rainer ; Hiergeist, Andreas

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 30 Nov 2023 16:08

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Abstract

Background: Neurosteroids have recently gained in interest as a treatment strategy for affective disorders. Etifoxine is known for its dual mode of action, one of which is to stimulate endogenous neurosteroid synthesis. The gut microbiome has been studied in affective disorders, but it has not been investigated in the context of human etifoxine or neurosteroid interventions. Methods: We ...