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Impact of laparoscopic versus open surgery on humoral immunity in patients with colorectal cancer: a systematic review and meta-analysis

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Bohne, Annika ; Grundler, Elena ; Knüttel, Helge ; Völkel, Vinzenz ; Fürst, Alois
[img]License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 04 Jan 2024 07:36

This publication is part of the DEAL contract with Springer.


Background: Laparoscopic surgery (LS) is hypothesized to result in milder proinfammatory reactions due to less severe operative trauma, which may contribute to the observed clinical benefts after LS. However, previous systematic reviews and meta-analyses on the impact of LS on immunocompetence are outdated, limited and heterogeneous. Therefore, the humoral response after laparoscopic and open ...


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