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Grosch, Melanie ; Brunner, Katrin ; Ilyaskin, Alexandr V. ; Schober, Michael ; Staudner, Tobias ; Schmied, Denise ; Stumpp, Tina ; Schmidt, Kerstin N. ; Madej, M. Gregor ; Pessoa, Thaissa D. ; Othmen, Helga ; Kubitza, Marion ; Osten, Larissa ; de Vries, Uwe ; Mair, Magdalena M. ; Somlo, Stefan ; Moser, Markus ; Kunzelmann, Karl ; Ziegler, Christine ; Haerteis, Silke ; Korbmacher, Christoph ; Witzgall, Ralph

A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts

Article

Grosch, Melanie, Brunner, Katrin, Ilyaskin, Alexandr V. , Schober, Michael, Staudner, Tobias, Schmied, Denise, Stumpp, Tina, Schmidt, Kerstin N., Madej, M. Gregor , Pessoa, Thaissa D., Othmen, Helga, Kubitza, Marion, Osten, Larissa, de Vries, Uwe, Mair, Magdalena M. , Somlo, Stefan, Moser, Markus, Kunzelmann, Karl, Ziegler, Christine , Haerteis, Silke, Korbmacher, Christoph and Witzgall, Ralph (2021) A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts. Journal of Cell Science 134 (16).



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Details

Item typeArticle
Journal or Publication TitleJournal of Cell Science
PublisherCOMPANY BIOLOGISTS LTD
Place of PublicationCAMBRIDGE
Volume134
Number of Issue or Book Chapter16
Date2021
Date of publication29 Feb 2024 12:14
InstitutionsBiology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Christine Ziegler
Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann
Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie > Prof. Dr. Ralph Witzgall
Identification Number
ValueType
10.1242/jcs.259013DOI
KeywordsKIDNEY; CILIA; PKD2; IDENTIFICATION; CILIOGENESIS; INHIBITION; MEMBRANE; SUBUNIT; CELLS; Polycystin-2; PKD2; Autosomal-dominant polycystic kidney disease; Knock-in mice; Electrophysiology; Xenopus laevis oocytes; Tubular diameter; Lumen formation
Dewey Decimal Classification500 Science > 570 Life sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID55841

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