A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts
Article
Grosch, Melanie, Brunner, Katrin, Ilyaskin, Alexandr V.
, Schober, Michael, Staudner, Tobias, Schmied, Denise, Stumpp, Tina, Schmidt, Kerstin N., Madej, M. Gregor
, Pessoa, Thaissa D., Othmen, Helga, Kubitza, Marion, Osten, Larissa, de Vries, Uwe, Mair, Magdalena M.
, Somlo, Stefan, Moser, Markus, Kunzelmann, Karl, Ziegler, Christine
, Haerteis, Silke, Korbmacher, Christoph and Witzgall, Ralph
(2021)
A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts.
Journal of Cell Science 134 (16).
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| Item type | Article | ||||
| Journal or Publication Title | Journal of Cell Science | ||||
| Publisher | COMPANY BIOLOGISTS LTD | ||||
| Place of Publication | CAMBRIDGE | ||||
| Volume | 134 | ||||
| Number of Issue or Book Chapter | 16 | ||||
| Date | 2021 | ||||
| Date of publication | 29 Feb 2024 12:14 | ||||
| Institutions | Biology, Preclinical Medicine > Institut für Biophysik und physikalische Biochemie > Prof. Dr. Christine Ziegler Biology, Preclinical Medicine > Institut für Physiologie > Prof. Dr. Karl Kunzelmann Biology, Preclinical Medicine > Institut für Anatomie > Lehrstuhl für Molekulare und zelluläre Anatomie > Prof. Dr. Ralph Witzgall | ||||
| Identification Number |
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| Keywords | KIDNEY; CILIA; PKD2; IDENTIFICATION; CILIOGENESIS; INHIBITION; MEMBRANE; SUBUNIT; CELLS; Polycystin-2; PKD2; Autosomal-dominant polycystic kidney disease; Knock-in mice; Electrophysiology; Xenopus laevis oocytes; Tubular diameter; Lumen formation | ||||
| Dewey Decimal Classification | 500 Science > 570 Life sciences | ||||
| Status | Published | ||||
| Refereed | Yes, this version has been refereed | ||||
| Created at the University of Regensburg | Yes | ||||
| Item ID | 55841 |
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