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Alkylated epidermal creatine kinase as a biomarker for sulfur mustard exposure: comparison to adducts of albumin and DNA in an in vivo rat study

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Steinritz, Dirk ; Lüling, Robin ; Siegert, Markus ; Herbert, Julia ; Mückter, Harald ; Taeger, Christian D. ; Gudermann, Thomas ; Dietrich, Alexander ; Thiermann, Horst ; John, Harald
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Date of publication of this fulltext: 29 Feb 2024 12:28


Sulfur mustard (SM) is a chemical warfare agent which use is banned under international law and that has been used recently in Northern Iraq and Syria by the so-called Islamic State. SM induces the alkylation of endogenous proteins like albumin and hemoglobin thus forming covalent adducts that are targeted by bioanalytical methods for the verification of systemic poisoning. We herein report a ...


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