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CyFi-MAP: an interactive pathway-based resource for cystic fibrosis

Pereira, Catarina ; Mazein, Alexander ; Farinha, Carlos M. ; Gray, Michael A. ; Kunzelmann, Karl ; Ostaszewski, Marek ; Balaur, Irina ; Amaral, Margarida D. ; Falcao, Andre O.


Cystic fibrosis (CF) is a life-threatening autosomal recessive disease caused by more than 2100 mutations in the CF transmembrane conductance regulator (CFTR) gene, generating variability in disease severity among individuals with CF sharing the same CFTR genotype. Systems biology can assist in the collection and visualization of CF data to extract additional biological significance and find ...


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