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High Androgen Receptor mRNA Expression Is Associated with Improved Outcome in Patients with High-Risk Non-Muscle-Invasive Bladder Cancer

Sikic, Danijel ; Taubert, Helge ; Wirtz, Ralph M. ; Breyer, Johannes ; Eckstein, Markus ; Weyerer, Veronika ; Kubon, Jennifer ; Erben, Philipp ; Bolenz, Christian ; Burger, Maximilian ; Hartmann, Arndt ; Wullich, Bernd ; Wach, Sven ; Keck, Bastian


The role of the androgen receptor (AR) in non-muscle-invasive bladder cancer (NMIBC) remains controversial. We retrospectively analyzed the mRNA expression of AR using RT-qPCR in 95 patients with high-risk NMIBC treated with a bladder-sparing approach and correlated AR with clinical data and recurrence-free survival (RFS), cancer-specific survival (CSS), and overall survival (OS). The mRNA ...


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