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Potential Candidates for Focal Therapy in Prostate Cancer in the Era of Magnetic Resonance Imaging–targeted Biopsy: A Large Multicenter Cohort Study

von Hardenberg, Jost ; Borkowetz, Angelika ; Siegel, Fabian ; Kornienko, Kira ; Westhoff, Niklas ; Jordan, Tobias B. ; Hoffmann, Manuela ; Drerup, Martin ; Lieb, Verena ; Taymoorian, Kasra ; Schostak, Martin ; Ganzer, Roman ; Höfner, Thomas ; Cash, Hannes ; Bruendl, Johannes


Background: Focal therapy (FT) with its favorable side-effect profile represents an option between active surveillance and traditional whole-gland treatment in localized prostate cancer (PCa). Consensus statements recommend eligibility criteria based on magnetic resonance imaging (MRI)-targeted and systematic combination biopsy. Objective: To estimate the future potential of FT by analyzing the ...


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