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Prognostic impact of gross tumor volume during radical radiochemotherapy of locally advanced non-small cell lung cancer—results from the NCT03055715 multicenter cohort study of the Young DEGRO Trial Group

Ostheimer, C. ; Mäurer, M. ; Ebert, N. ; Schmitt, D. ; Krug, D. ; Baumann, R. ; Henkenberens, C. ; Giordano, F. A. ; Sautter, L. ; López, Guerra ; Fleischmann, D. F. ; Niyazi, M. ; Käsmann, L. ; Kaul, D. ; Thieme, A. H. ; Billiet, C. ; Dobiasch, S. ; Arnold, C. R. ; Oertel, M. ; Haussmann, J. ; Gauer, T. ; Goy, Y. ; Suess, C. ; Ziegler, S. ; Panje, C. M. ; Baues, C. ; Trommer, M. ; Skripcak, T. ; Medenwald, D.




Abstract

Background In radical radiochemotherapy (RCT) of inoperable non-small-cell lung cancer (NSCLC) typical prognostic factors include T- and N-stage, while there are still conflicting data on the prognostic relevance of gross tumor volume (GTV) and particularly its changes during RCT. The NCT03055715 study of the Young DEGRO working group of the German Society of Radiation Oncology (DEGRO) evaluated ...

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