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Uncovering the curcumin solubilization ability of selected natural deep eutectic solvents based on quaternary ammonium compounds

Huber, Verena ; Hioe, Johnny ; Touraud, Didier ; Kunz, Werner


The solubility of curcumin in ethanolic solutions can be increased twentyfold through the addition of natural deep eutectic solvents (NADES). Instead of only screening nine different NADES based on choline chloride, betaine, and carnitine mixed with lactic, levulinic, and pyruvic acid in terms of their solving ability, they were investigated regarding the mechanism of solvation as well. The ...


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