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Continuous intra-arterial nimodipine infusion as rescue treatment of severe refractory cerebral vasospasm after aneurysmal subarachnoid hemorrhage

Anthofer, Judith ; Bele, Sylvia ; Wendl, Christina ; Kieninger, Martin ; Zeman, Florian ; Bruendl, Elisabeth ; Schmidt, Nils-Ole ; Schebesch, Karl-Michael


Severe refractory cerebral vasospasm (CV) is a major cause of disability and death in patients with aneurysmal subarachnoid hemorrhage (SAH). One rescue therapy in selected patients is intra-arterial nimodipine, either given as a single shot or as continuous infusion. To evaluate treatment efficacy, we analyzed outcome factors such as the incidence of craniectomy, ventriculo-peritonial (VP) ...


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