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Singh, Gurpreet ; Liu, Peng ; Yao, Katherine R. ; Strasser, Jessica M. ; Hlynialuk, Chris ; Leinonen-Wright, Kailee ; Teravskis, Peter J. ; Choquette, Jessica M. ; Ikramuddin, Junaid ; Bresinsky, Merlin ; Nelson, Kathryn M. ; Liao, Dezhi ; Ashe, Karen H. ; Walters, Michael A. ; Pockes, Steffen

Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy

Singh, Gurpreet, Liu, Peng, Yao, Katherine R., Strasser, Jessica M., Hlynialuk, Chris, Leinonen-Wright, Kailee, Teravskis, Peter J., Choquette, Jessica M., Ikramuddin, Junaid, Bresinsky, Merlin, Nelson, Kathryn M., Liao, Dezhi, Ashe, Karen H., Walters, Michael A. and Pockes, Steffen (2022) Caspase-2 Inhibitor Blocks Tau Truncation and Restores Excitatory Neurotransmission in Neurons Modeling FTDP-17 Tauopathy. ACS Chemical Neuroscience 13 (10), pp. 1549-1557.

Date of publication of this fulltext: 29 Feb 2024 12:52
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Item typeArticle
Journal or Publication TitleACS Chemical Neuroscience
Publisher:AMER CHEMICAL SOC
Place of Publication:WASHINGTON
Volume:13
Number of Issue or Book Chapter:10
Page Range:pp. 1549-1557
Date2022
InstitutionsChemistry and Pharmacy > Institute of Pharmacy > Pharmaceutical/Medicinal Chemistry I (Prof. Elz)
Identification Number
ValueType
10.1021/acschemneuro.2c00100DOI
KeywordsCELL-DEATH; FRONTOTEMPORAL DEMENTIA; DENDRITIC SPINES; APOPTOSIS; MISLOCALIZATION; DYSFUNCTION; MUTATION; FAMILY; NEDD2; GENE; Caspase-2; Alzheimer ? s disease; neurodegenerative disorders; tauopathies; dementia
Dewey Decimal Classification500 Science > 540 Chemistry & allied sciences
StatusPublished
RefereedYes, this version has been refereed
Created at the University of RegensburgYes
Item ID57232

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