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SARS-CoV-2 infects human cardiomyocytes promoted by inflammation and oxidative stress

Tangos, Melina ; Budde, Heidi ; Kolijn, Detmar ; Sieme, Marcel ; Zhazykbayeva, Saltanat ; Lódi, Mária ; Herwig, Melissa ; Gömöri, Kamilla ; Hassoun, Roua ; Robinson, Emma Louise ; Meister, Toni Luise ; Jaquet, Kornelia ; Kovács, Árpád ; Mustroph, Julian ; Evert, Katja ; Babel, Nina ; Fagyas, Miklós ; Lindner, Diana ; Püschel, Klaus ; Westermann, Dirk ; Mannherz, Hans Georg ; Paneni, Francesco ; Pfaender, Stephanie ; Tóth, Attila ; Mügge, Andreas ; Sossalla, Samuel ; Hamdani, Nazha



Zusammenfassung

Introduction: The respiratory illness triggered by severe acute respiratory syndrome virus-2 (SARS-CoV-2) is often particularly serious or fatal amongst patients with pre-existing heart conditions. Although the mechanisms underlying SARS-CoV-2-related cardiac damage remain elusive, inflammation (i.e. 'cytokine storm') and oxidative stress are likely involved. Methods and results: Here we sought ...

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