Go to content
UR Home

Directing HIV-1 for degradation by non-target cells, using bi-specific single-chain llama antibodies

Stam, Jord C. ; de Maat, Steven ; de Jong, Dorien ; Arens, Mathia ; van Lint, Fenna ; Gharu, Lavina ; van Roosmalen, Mark H. ; Roovers, Rob C. ; Strokappe, Nika M. ; Wagner, Ralf ; Kliche, Alexander ; de Haard, Hans J. ; van Bergen en Henegouwen, Paul M. ; Nijhuis, Monique ; Verrips, C. Theo



Abstract

While vaccination against HIV-1 has been so far unsuccessful, recently broadly neutralizing antibodies (bNAbs) against HIV-1 envelope glycoprotein were shown to induce long-term suppression in the absence of antiretroviral therapy in patients with antibody-sensitive viral reservoirs. The requirement of neutralizing antibodies indicates that the antibody mediated removal (clearance) of HIV-1 in ...

plus


Owner only: item control page
  1. Homepage UR

University Library

Publication Server

Contact:

Publishing: oa@ur.de
0941 943 -4239 or -69394

Dissertations: dissertationen@ur.de
0941 943 -3904

Research data: datahub@ur.de
0941 943 -5707

Contact persons