Sohl, Julian ; Hartmann, Ann-Kathrin ; Hahlbrock, Jennifer ; Bartneck, Joschka ; Stassen, Michael ; Klein, Matthias ; Bros, Matthias ; Grabbe, Stephan ; Marini, Federico 
; Woods, Kevin ; Guezguez, Borhane ; Mack, Matthias ; Schild, Hansjörg ; Muth, Sabine ; Melchior, Felix ; Probst, Hans Christian ; Langguth, Peter ; Radsak, Markus P.
; Woods, Kevin ; Guezguez, Borhane ; Mack, Matthias ; Schild, Hansjörg ; Muth, Sabine ; Melchior, Felix ; Probst, Hans Christian ; Langguth, Peter ; Radsak, Markus P. 
Zusammenfassung
Transcutaneous immunization (TCI) utilizing the TLR7 agonist imiquimod (IMQ-TCI) induces T cell-driven protective immunity upon application onto intact skin. In our present work, we combine the anti-psoriatic agent dithranol with IMQ-TCI to boost vaccination efficacy (Dithranol/IMQ-based transcutaneous vaccination (DIVA)). Using ovalbumin-derived peptides as model antigens in mice, DIVA induced ...
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