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On the uncertainty of the correlation between nanoparticle avidity and biodistribution

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Zimmer, Oliver ; Goepferich, Achim
Date of publication of this fulltext: 12 Mar 2024 09:40


The specific delivery of a drug to its site of action also known as targeted drug delivery is a topic in the field of pharmaceutics studied for decades. One approach extensively investigated in this context is the use ligand functionalized nanoparticles. These particles are modified to carry receptor specific ligands, enabling them to accumulate at a desired target site. However, while this ...


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