On the uncertainty of the correlation between nanoparticle avidity and biodistribution

URN to cite this document:: urn:nbn:de:bvb:355-epub-578858
DOI to cite this document:: 10.5283/epub.57885

Zimmer, Oliver

; Goepferich, Achim

License: Creative Commons Attribution Non-commercial No Derivatives 4.0
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Date of publication of this fulltext: 12 Mar 2024 09:40

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Abstract

The specific delivery of a drug to its site of action also known as targeted drug delivery is a topic in the field of pharmaceutics studied for decades. One approach extensively investigated in this context is the use ligand functionalized nanoparticles. These particles are modified to carry receptor specific ligands, enabling them to accumulate at a desired target site. However, while this ...