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Prospective Cohort Study of Soluble Urokinase Plasminogen Activation Receptor and Cardiovascular Events in Patients With CKD

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Sommerer, Claudia ; Müller-Krebs, Sandra ; Nadal, Jennifer ; Schultheiss, Ulla T. ; Friedrich, Nele ; Nauck, Matthias ; Schmid, Matthias ; Nußhag, Christian ; Reiser, Jochen ; Eckardt, Kai-Uwe ; Zeier, Martin ; Hayek, Salim S. ; Oefner, Peter J. ; Gronwald, Wolfram
Date of publication of this fulltext: 08 Apr 2024 07:08


Introduction: Soluble urokinase plasminogen activation receptor (suPAR) is an immune-derived pathogenic factor for kidney and atherosclerotic disease. Whether the association between suPAR and cardiovascular (CV) outcomes is dependent on the severity of underlying kidney disease is unclear. Methods: We measured serum suPAR levels in 4994 participants (mean age 60 years; 60% men; 36% with ...


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