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The ex vivo perfused mouse adrenal gland—a new model to study aldosterone secretion

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Plain, Allein ; Knödl, Laura ; Tegtmeier, Ines ; Bandulik, Sascha ; Warth, Richard
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Date of publication of this fulltext: 04 Apr 2024 05:56

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Aldosterone is a steroid hormone that is important for maintaining the volume and ionic composition of extracellular fluids and is produced in the zona glomerulosa of the adrenal cortex. The basic mechanisms controlling aldosterone secretion are known. However, more detailed studies on the regulation of aldosterone secretion often fail due to the lack of suitable models: although secretion can be ...


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