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- URN zum Zitieren dieses Dokuments:
- urn:nbn:de:bvb:355-epub-586306
- DOI zum Zitieren dieses Dokuments:
- 10.5283/epub.58630
Zusammenfassung
An important question in cell biology is how cytoskeletal proteins evolved and drove the development of novel structures and functions. Here we address the origin of SPIRE actin nucleators. Mammalian SPIREs work with RAB GTPases, formin (FMN)-subgroup actin assembly proteins and class-5 myosin (MYO5) motors to transport organelles along actin filaments towards the cell membrane. However, the ...