Establishment of closed 35S ribosomal RNA gene chromatin in stationary Saccharomyces cerevisiae cells

URN to cite this document:: urn:nbn:de:bvb:355-epub-593534
DOI to cite this document:: 10.5283/epub.59353

Babl, Virginia-Lorena ; Girke, Philipp ; Kruse, Sebastian ; Pinz, Sophia Charlotte

; Hannig, Katharina ; Schächner, Christopher ; Hergert, Kristin ; Wittner, Manuel ; Seufert, Wolfgang

; Milkereit, Philipp

; Tschochner, Herbert ; Griesenbeck, Joachim

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 09 Oct 2024 11:06

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Abstract

As a first step in eukaryotic ribosome biogenesis RNA polymerase (Pol) I synthesizes a large ribosomal RNA (rRNA) precursor from multicopy rRNA gene loci. This process is essential for cellular growth and regulated in response to the cell’s physiological state. rRNA gene transcription is downregulated upon growth to stationary phase in the yeast Saccharomyces cerevisiae. This reduction correlates ...