LoDEI: a robust and sensitive tool to detect transcriptome-wide differential A-to-I editing in RNA-seq data

URN to cite this document:: urn:nbn:de:bvb:355-epub-594312
DOI to cite this document:: 10.5283/epub.59431

Torkler, Phillipp ; Sauer, Marina ; Schwartz, Uwe

; Corbacioglu, Selim

; Sommer, Gunhild

; Heise, Tilman

License: Creative Commons Attribution 4.0
PDF - Published Version
(1MB)

Date of publication of this fulltext: 23 Oct 2024 12:04

Alternative links to fulltext:DOI Publisher

Details

Preview

Export bibliographical data

Abstract

RNA editing is a highly conserved process. Adenosine deaminase acting on RNA (ADAR) mediated deamination of adenosine (A-to-I editing) is associated with human disease and immune checkpoint control. Functional implications of A-to-I editing are currently of broad interest to academic and industrial research as underscored by the fast-growing number of clinical studies applying base editors as ...