Increased CRF-R1 transmission in the nucleus accumbens shell facilitates maternal neglect in lactating rats and mediates anxiety-like behaviour in a sex-specific manner

URN to cite this document:: urn:nbn:de:bvb:355-epub-598009
DOI to cite this document:: 10.5283/epub.59800

Sanson, Alice

; Demarchi, Luisa

; Rocaboy, Emma ; Bosch, Oliver J.

License: Creative Commons Attribution Non-commercial 4.0
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Date of publication of this fulltext: 17 Dec 2024 06:48

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Abstract

During the transition to motherhood, complex brain adaptations occur to ensure adequate maternal responses to offspring’ needs accompanied by reduced anxiety. Among others, the corticotropin-releasing factor (CRF) and oxytocin (OXT) systems have emerged as crucial regulators of these essential postpartum adaptations. Here, we investigated their roles within the nucleus accumbens shell (NAcSh), a ...