Fecal Nervonic Acid as a Biomarker for Diagnosing and Monitoring Inflammatory Bowel Disease

URN to cite this document:: urn:nbn:de:bvb:355-epub-598310
DOI to cite this document:: 10.5283/epub.59831

Kunst, Claudia ; Elger, Tanja ; Loibl, Johanna ; Huss, Muriel ; Kandulski, Arne

; Krautbauer, Sabrina ; Müller, Martina ; Liebisch, Gerhard

; Tews, Hauke Christian ; Buechler, Christa

License: Creative Commons Attribution 4.0
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Date of publication of this fulltext: 18 Dec 2024 14:39

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Abstract

Background/Objectives: Inflammatory bowel disease (IBD) is a chronic immune-mediated pathology associated with the dysregulation of lipid metabolism. The administration of nervonic acid, a very long-chain fatty acid, has been shown to improve colonic inflammation in a mouse model of colitis. Our study aimed to quantify fecal levels of nervonic acid, as well as the very long-chain fatty acids, ...