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Unique transposon landscapes are pervasive acrossDrosophila melanogastergenomes

Rahman, Reazur ; Chirn, Gung-wei ; Kanodia, Abhay ; Sytnikova, Yuliya A. ; Brembs, Björn ; Bergman, Casey M. ; Lau, Nelson C.



Zusammenfassung

To understand how transposon landscapes (TLs) vary across animal genomes, we describe a new method called the Transposon Insertion and Depletion AnaLyzer (TIDAL) and a database of >300 TLs in Drosophila melanogaster (TIDAL-Fly). Our analysis reveals pervasive TL diversity across cell lines and fly strains, even for identically named sub-strains from different laboratories such as the ISO1 strain ...

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