Zusammenfassung
The use of angiotensin receptor blockers (ARBs) for treatment of ocular diseases associated with neovascularizations, such as proliferative diabetic retinopathy, shows tremendous promise but is presently limited due to short intravitreal half-life. Conjugation of ARE molecules to branched polymers could vastly augment their therapeutic efficacy. EXP3174, a potent non-peptide ARE, was conjugated ...
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