Lejeune, Alice ; Cremer, Malte ; von Bernuth, Horst ; Edelmann, Anke ; Modrow, Susanne ; Bührer, Christoph
Alternative Links zum Volltext:DOIVerlag
| Dokumentenart: | Artikel |
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| Titel eines Journals oder einer Zeitschrift: | European Journal of Pediatrics |
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| Verlag: | SPRINGER |
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| Ort der Veröffentlichung: | NEW YORK |
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| Band: | 173 |
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| Nummer des Zeitschriftenheftes oder des Kapitels: | 12 |
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| Seitenbereich: | S. 1723-1726 |
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| Datum: | 2014 |
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| Institutionen: | Medizin > Lehrstuhl für Medizinische Mikrobiologie und Hygiene |
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| Identifikationsnummer: | | Wert | Typ |
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| 10.1007/s00431-014-2420-5 | DOI |
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| Stichwörter / Keywords: | PREGNANCY; Parvovirus B19; Congenital pure red cell aplasia; IVIG; Neonate; Anemia |
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| Dewey-Dezimal-Klassifikation: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin |
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| Status: | Veröffentlicht |
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| Begutachtet: | Ja, diese Version wurde begutachtet |
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| An der Universität Regensburg entstanden: | Ja |
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| Dokumenten-ID: | 60938 |
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Web of Science
Zusammenfassung
We report the course of dicygotic twins born preterm after 29 (4)/(7) weeks of gestation due to congenital Parvovirus B19 infection causing fetal hydrops with severe anemia in one infant in whom intrauterine transfusion was impossible to perform and high levels of viremia in both infants. After being discharged, they were readmitted at 3 months of age with critical aplastic crisis. Therapy with ...
Zusammenfassung
We report the course of dicygotic twins born preterm after 29 (4)/(7) weeks of gestation due to congenital Parvovirus B19 infection causing fetal hydrops with severe anemia in one infant in whom intrauterine transfusion was impossible to perform and high levels of viremia in both infants. After being discharged, they were readmitted at 3 months of age with critical aplastic crisis. Therapy with intravenous immunoglobulin infusion resulted in decreasing viremia followed by stable hemoglobin levels in both infants. Conclusion: Intravenous immunoglobulin treatment of congenital pure red cell aplasia due to Parvovirus B19 infection in preterm infants seems to be effective to introduce viral remission and to normalize erythropoiesis.