Olden, Matthias ; Corre, Tanguy ; Hayward, Caroline ; Toniolo, Daniela ; Ulivi, Sheila ; Gasparini, Paolo ; Pistis, Giorgio ; Hwang, Shih-Jen ; Bergmann, Sven ; Campbell, Harry ; Cocca, Massimiliano 
; Gandin, Ilaria ; Girotto, Giorgia ; Glaudemans, Bob ; Hastie, Nicholas D. ; Loffing, Johannes ; Polasek, Ozren ; Rampoldi, Luca ; Rudan, Igor ; Sala, Cinzia ; Traglia, Michela ; Vollenweider, Peter ; Vuckovic, Dragana ; Youhanna, Sonia ; Weber, Julien ; Wright, Alan F. ; Kutalik, Zoltán ; Bochud, Murielle ; Fox, Caroline S. ; Devuyst, Olivier
; Gandin, Ilaria ; Girotto, Giorgia ; Glaudemans, Bob ; Hastie, Nicholas D. ; Loffing, Johannes ; Polasek, Ozren ; Rampoldi, Luca ; Rudan, Igor ; Sala, Cinzia ; Traglia, Michela ; Vollenweider, Peter ; Vuckovic, Dragana ; Youhanna, Sonia ; Weber, Julien ; Wright, Alan F. ; Kutalik, Zoltán ; Bochud, Murielle ; Fox, Caroline S. ; Devuyst, Olivier 
Abstract
Uromodulin is expressed exclusively in the thick ascending limb and is the most abundant protein excreted in normal urine. Variants in UMOD, which encodes uromodulin, are associated with renal function, and urinary uromodulin levels may be a biomarker for kidney disease. However, the genetic factors regulating uromodulin excretion are unknown. We conducted a meta-analysis of urinary uromodulin ...
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