Progression types after antiangiogenic therapy are related to outcome in recurrent glioblastoma

Nowosielski, Martha ; Wiestler, Benedikt ; Goebel, Georg ; Hutterer, Markus ; Schlemmer, Heinz P. ; Stockhammer, Günther ; Wick, Wolfgang ; Bendszus, Martin ; Radbruch, Alexander

Alternative Links zum Volltext:DOI Verlag

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Objective:This retrospective study analyzed whether the type of radiologic progression, classified according to contrast enhancement on MRI T1-weighted sequences and changes in T2-hyperintense signal, is relevant for outcome in patients with progressive glioblastoma (pGB) treated with bevacizumab.Methods:MRI scans of 83 patients with pGB treated with bevacizumab were evaluated prior to and at ...